Harrison's Manual of Medicine 17/e

Table 126-2: Hemodynamic Complications in Acute MI

Table 126-2

Condition

Cardiac Index, (L/min)/m2

PCW, mmHg

Systolic bp, mmHg

Treatment

Uncomplicated

>2.5

≤18

>100

Hypovolemia

< 2.5

< 15

< 100

Successive boluses of normal saline

In setting of inferior wall MI, consider RV infarction (esp. if RA pressure >10)

Volume overload

>2.5

>20

>100

Diuretic (e.g., furosemide 10–20 mg IV)

Nitroglycerin, topical paste or IV (Table 126-1)

LV failure

< 2.5

>20

>100

Diuretic (e.g., furosemide 10–20 mg IV)

IV nitroglycerin (or if hypertensive, use IV nitroprusside)

Severe LV failure

< 2.5

>20

< 100

If bp ≥90: IV dobutamine ± IV nitroglycerin or sodium nitroprusside

If bp < 90: IV dopamine

If accompanied by pulmonary edema: attempt diuresis with IV furosemide; may be limited by hypotension

If new systolic murmur present, consider acute VSD or mitral regurgitation

Cardiogenic shock

< 2.2

>20

< 90 with oliguria and confusion

IV dopamine

Intraaortic balloon pump

Reperfusion by PCI or CABG may be life-saving

Note: PCW, pulmonary artery wedge pressure; RV, right ventricle; LV, left ventricle; PCI, percutaneous coronary intervention; VSD, ventricular septal defect; CABG, coronary artery bypass graft.

Chapter:
ST-Segment Elevation Myocardial Infarction (STEMI)

Table 126-2: Hemodynamic Complications in Acute MI has been found in Harrison's Manual of Medicine 17/e

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